Search on: APC3 SUBUNIT, ANAPHASE-PROMOTING COMPLEX-CYCLOSOME 
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Descriptor English:   Apc3 Subunit, Anaphase-Promoting Complex-Cyclosome 
Descriptor Spanish:   Subunidad Apc3 del Ciclosoma-Complejo Promotor de la Anafase 
Descriptor Portuguese:   Subunidade Apc3 do Ciclossomo-Complexo Promotor de Anáfase 
Synonyms English:   Anapc3
Apc3 Subunit, Anaphase-Promoting Complex
CDC27 Protein
Apc3 Subunit, Anaphase Promoting Complex
Apc3 Subunit, Anaphase Promoting Complex Cyclosome  
Tree Number:   D08.811.464.938.750.092.875
D12.776.167.024.875
Definition English:   A highly evolutionarily conserved subunit of the anaphase-promoting complex (APC-C) containing multiple 34-amino-acid tetratricopeptide repeats. These domains, also found in Apc subunits 6, 7, and 8, have been shown to mediate protein-protein interactions, suggesting that Apc3 may assist in coordinating the juxtaposition of the catalytic and substrate recognition module subunits relative to co-activators and APC-C inhibitors. 
History Note English:   2014 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   55277 
Unique Identifier:   D064191 

Occurrence in VHL:
 

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